GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rela | increases expression | ISO | Rela (Mus musculus) | 6480464 | CTD | Silicon Dioxide results in increased expression of RELA mRNA; Silicon Dioxide results in increased expression of RELA protein | PMID:25949234 PMID:32017981 PMID:37075931 | Rela | increases phosphorylation | ISO | RELA (Homo sapiens) | 6480464 | CTD | Silicon Dioxide analog results in increased phosphorylation of RELA protein; Silicon Dioxide results in increased phosphorylation of RELA protein | PMID:24844442 PMID:34653535 | Rela | increases phosphorylation | ISO | Rela (Mus musculus) | 6480464 | CTD | Silicon Dioxide results in increased phosphorylation of RELA protein | PMID:30698894 | Rela | multiple interactions | ISO | RELA (Homo sapiens) | 6480464 | CTD | RELA mutant form inhibits the reaction [Silicon Dioxide analog results in increased secretion of CXCL8 protein]; RELA mutant form inhibits the reaction [Silicon Dioxide analog results in increased secretion of IL6 protein] | PMID:24844442 | Rela | multiple interactions | ISO | Rela (Mus musculus) | 6480464 | CTD | LIAS protein promotes the reaction [Silicon Dioxide results in increased expression of RELA protein]; Vitamin D inhibits the reaction [Silicon Dioxide results in increased phosphorylation of RELA protein] | PMID:30698894 PMID:32017981 | | ||||||||||||||||||||||
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