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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc7a11
Name: solute carrier family 7 member 11
Acc ID: CHEBI:30563
Term: silicon dioxide
Definition: A silicon oxide made up of linear triatomic molecules in which a silicon atom is covalently bonded to two oxygens.
Chemical ID: MESH:D012822
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc7a11decreases expressionISOSlc7a11 (Mus musculus)6480464CTDSilicon Dioxide results in decreased expression of SLC7A11 proteinPMID:37075931
Slc7a11increases expressionISOSlc7a11 (Mus musculus)6480464CTDSilicon Dioxide results in increased expression of SLC7A11 mRNAPMID:19073995 PMID:29341224
Slc7a11multiple interactionsISOSlc7a11 (Mus musculus)6480464CTDerastin promotes the reaction [Silicon Dioxide results in decreased expression of SLC7A11 protein]; KN 93 inhibits the reaction [Silicon Dioxide results in decreased expression of SLC7A11 protein]; WNT5A protein promotes the reaction [Silicon Dioxide results in decreased expression of SLC7A11 protein]PMID:37075931
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