GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Aqp2 | decreases expression | EXP | | 6480464 | CTD | Lithium results in decreased expression of AQP2 mRNA; Lithium results in decreased expression of AQP2 protein | PMID:10966935 PMID:12472779 PMID:14613889 PMID:15153756 PMID:15504936 PMID:16434572 PMID:18296634 PMID:7535800 | Aqp2 | increases expression | EXP | | 6480464 | CTD | Lithium results in increased expression of AQP2 protein | PMID:19244398 | Aqp2 | multiple interactions | EXP | | 6480464 | CTD | [Aldosterone co-treated with Lithium] affects the expression of AQP2 protein; [Spironolactone co-treated with Lithium] affects the expression of AQP2 protein; Hydrochlorothiazide inhibits the reaction [Lithium results in decreased expression of AQP2 protein] | PMID:15504936 PMID:16159898 | Aqp2 | decreases expression | ISO | Aqp2 (Mus musculus) | 6480464 | CTD | Lithium results in decreased expression of AQP2 protein | PMID:25006961 | Aqp2 | multiple interactions | ISO | Aqp2 (Mus musculus) | 6480464 | CTD | Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 mRNA]; Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 protein]; PRKCA gene mutant form inhibits the reaction [Lithium results in decreased expression of AQP2 protein] | PMID:16495377 PMID:25006961 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |