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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70500 Species: Rattus norvegicus RGD Object: Gene Symbol: Mapk1 Name: mitogen activated protein kinase 1

Acc ID: CHEBI:30045 Term: divanadium pentaoxide Definition: A vanadium oxide that has formula O5V2. CasRN: 1314-62-1 Chemical ID: MESH:C066075

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases phosphorylation	ISO	RGD:732503	6480464	CTD	vanadium pentoxide results in increased phosphorylation of MAPK1 protein	PMID:12376484
increases activity	ISO	RGD:732502	6480464	CTD	vanadium pentoxide results in increased activity of MAPK1 protein	PMID:12676768