GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rela | decreases expression | EXP | | 6480464 | CTD | arsenite results in decreased expression of RELA protein | PMID:29324385 | Rela | multiple interactions | EXP | | 6480464 | CTD | Selenium inhibits the reaction [arsenite results in decreased expression of RELA protein] | PMID:29324385 | Rela | affects localization | ISO | RELA (Homo sapiens) | 6480464 | CTD | arsenite affects the localization of RELA protein | PMID:26677073 | Rela | increases expression | ISO | Rela (Mus musculus) | 6480464 | CTD | arsenite results in increased expression of RELA protein | PMID:37442281 | Rela | increases phosphorylation | ISO | RELA (Homo sapiens) | 6480464 | CTD | arsenite results in increased phosphorylation of RELA protein | PMID:23469214 PMID:24704393 PMID:30177839 | Rela | increases phosphorylation | ISO | Rela (Mus musculus) | 6480464 | CTD | arsenite results in increased phosphorylation of RELA protein | PMID:22387281 | Rela | multiple interactions | ISO | RELA (Homo sapiens) | 6480464 | CTD | 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [arsenite promotes the reaction [RELA protein binds to MIR21 promoter]]; [sodium arsenite results in increased abundance of arsenite] which affects the localization of RELA protein; arsenite promotes the reaction [RELA protein binds to CREBBP protein]; arsenite promotes the reaction [RELA protein binds to MIR21 promoter]; arsenite results in increased phosphorylation of and affects the localization of RELA protein; arsenite results in increased phosphorylation of and results in increased activity of RELA protein; CAT protein inhibits the reaction [arsenite results in increased phosphorylation of RELA protein]; Decitabine inhibits the reaction [arsenite results in increased phosphorylation of RELA protein]; Heparin inhibits the reaction [arsenite affects the localization of RELA protein]; HSPA9 protein promotes the reaction [arsenite promotes the reaction [RELA protein binds to CREBBP protein]]; MIRLET7C mRNA inhibits the reaction [arsenite results in increased phosphorylation of RELA protein]; RELA mutant form inhibits the reaction [arsenite results in decreased expression of PDCD4 protein]; RELA mutant form inhibits the reaction [arsenite results in decreased expression of PTEN protein]; RELA mutant form inhibits the reaction [arsenite results in decreased expression of SPRY1 protein]; RELA mutant form inhibits the reaction [arsenite results in increased expression of MIR21 mRNA]; RELA mutant form inhibits the reaction [arsenite results in increased phosphorylation of MAPK1 protein]; RELA mutant form inhibits the reaction [arsenite results in increased phosphorylation of MAPK3 protein]; RELA protein inhibits the reaction [arsenite promotes the reaction [TP53 protein binds to CREBBP protein]]; RELA protein inhibits the reaction [arsenite results in increased phosphorylation of and results in increased localization of and results in increased activity of TP53 protein]; RELA protein promotes the reaction [arsenite results in increased expression of HSPA9 mRNA]; RELA protein promotes the reaction [arsenite results in increased expression of HSPA9 protein]; U 0126 inhibits the reaction [arsenite results in increased phosphorylation of and affects the localization of RELA protein] | PMID:20199942 PMID:22387281 PMID:22564430 PMID:24704393 PMID:26677073 | Rela | multiple interactions | ISO | Rela (Mus musculus) | 6480464 | CTD | CAT protein inhibits the reaction [arsenite results in increased phosphorylation of RELA protein] | PMID:22387281 | | ||||||||||||||||||||||
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