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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708540 Species: Rattus norvegicus RGD Object: Gene Symbol: Cxcl5 Name: chemokine (C-X-C motif) ligand 5

Acc ID: CHEBI:29866 Term: arsenite(3-) Definition: An arsenite ion resulting from the removal of all three protons from the hydroxy groups of arsenous acid. CasRN: 15502-74-6 Chemical ID: MESH:C015001

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:1552792	6480464	CTD	arsenite results in increased expression of CXCL5 mRNA	PMID:18929588
multiple interactions	ISO	RGD:1552792	6480464	CTD	TRP53 protein affects the reaction [arsenite results in increased expression of CXCL5 mRNA]	PMID:18929588