GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Krt10 | decreases expression | ISO | KRT10 (Homo sapiens) | 6480464 | CTD | arsenite results in decreased expression of KRT10 mRNA; arsenite results in decreased expression of KRT10 protein | PMID:18633435 | Krt10 | multiple interactions | ISO | KRT10 (Homo sapiens) | 6480464 | CTD | 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one promotes the reaction [[sodium arsenite results in increased abundance of arsenite] which results in decreased expression of KRT10 mRNA]; [sodium arsenite results in increased abundance of arsenite] which results in decreased expression of KRT10 mRNA; arsenite promotes the reaction [G3BP1 protein binds to KRT10 mRNA]; Hydrocortisone inhibits the reaction [[sodium arsenite results in increased abundance of arsenite] which results in decreased expression of KRT10 mRNA]; JAG1 protein inhibits the reaction [arsenite results in decreased expression of KRT10 mRNA]; RTKI cpd inhibits the reaction [arsenite results in decreased expression of KRT10 mRNA]; RTKI cpd inhibits the reaction [arsenite results in decreased expression of KRT10 protein]; U 0126 inhibits the reaction [[sodium arsenite results in increased abundance of arsenite] which results in decreased expression of KRT10 mRNA] | PMID:18633435 PMID:32076005 PMID:32406909 | | ||||||||||||||||||||||
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