GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tbx3 | decreases expression | ISO | Tbx3 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of TBX3 mRNA | PMID:22228805 PMID:23735875 PMID:27195522 | Tbx3 | decreases methylation | ISO | TBX3 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased methylation of TBX3 3' UTR; Benzo(a)pyrene results in decreased methylation of TBX3 exon | PMID:27901495 | Tbx3 | increases expression | ISO | TBX3 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of TBX3 mRNA | PMID:21802500 PMID:22316170 | Tbx3 | increases methylation | ISO | TBX3 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased methylation of TBX3 promoter | PMID:27901495 | |
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