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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708572
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Arl6ip5
Name: ADP-ribosylation factor like GTPase 6 interacting protein 5
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Arl6ip5increases expressionISOArl6ip5 (Mus musculus)6480464CTDBenzo(a)pyrene metabolite results in increased expression of ARL6IP5 mRNA; Benzo(a)pyrene results in increased expression of ARL6IP5 mRNAPMID:15034205 PMID:15894712 PMID:19770486 PMID:20713471 PMID:21715664 PMID:32553695
Arl6ip5multiple interactionsISOArl6ip5 (Mus musculus)6480464CTD[arsenite co-treated with Benzo(a)pyrene] results in increased expression of ARL6IP5 mRNA; [Benzo(a)pyrene results in increased activity of AHR protein] which results in increased expression of ARL6IP5 mRNAPMID:15894712 PMID:32553695
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