GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cd86 | increases expression | ISO | CD86 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of CD86 protein | PMID:21742781 | Cd86 | increases expression | ISO | Cd86 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of CD86 mRNA | PMID:22228805 | Cd86 | increases methylation | ISO | CD86 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased methylation of CD86 3' UTR; Benzo(a)pyrene results in increased methylation of CD86 5' UTR; Benzo(a)pyrene results in increased methylation of CD86 promoter | PMID:27901495 | Cd86 | multiple interactions | ISO | CD86 (Homo sapiens) | 6480464 | CTD | 1-aminobenzotriazole inhibits the reaction [Benzo(a)pyrene results in increased expression of CD86 protein] | PMID:21742781 | Cd86 | multiple interactions | ISO | Cd86 (Mus musculus) | 6480464 | CTD | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of CD86 mRNA] | PMID:22228805 | |
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