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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621870
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ugcg
Name: UDP-glucose ceramide glucosyltransferase
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ugcgmultiple interactionsEXP 6480464CTD[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of UGCG mRNAPMID:18711122
Ugcgdecreases expressionISOUGCG (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of UGCG mRNAPMID:20064835
Ugcgdecreases expressionISOUgcg (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of UGCG mRNAPMID:21569818
Ugcgincreases expressionISOUGCG (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of UGCG mRNAPMID:20106945
Ugcgincreases methylationISOUGCG (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of UGCG promoterPMID:27901495
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