GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Maoa | affects methylation | ISO | MAOA (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of MAOA intron; Benzo(a)pyrene affects the methylation of MAOA promoter | PMID:27901495 PMID:30157460 | Maoa | decreases expression | ISO | Maoa (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of MAOA mRNA | PMID:19770486 PMID:21569818 | Maoa | decreases expression | ISO | MAOA (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of MAOA mRNA | PMID:22316170 | Maoa | increases expression | ISO | Maoa (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of MAOA mRNA | PMID:20127859 | Maoa | increases methylation | ISO | MAOA (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased methylation of MAOA exon | PMID:27901495 | Maoa | multiple interactions | ISO | Maoa (Mus musculus) | 6480464 | CTD | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of MAOA mRNA | PMID:27858113 | |
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