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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3318
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb1b
Name: ATP-binding cassette, sub-family B member 1B
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb1bincreases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of ABCB1B mRNAPMID:24025706
Abcb1bmultiple interactionsEXP 6480464CTDBenzo(a)pyrene promotes the reaction [TNF protein results in increased expression of ABCB1B mRNA]; TNF protein promotes the reaction [Benzo(a)pyrene results in increased expression of ABCB1B mRNA]PMID:24025706
Abcb1baffects expressionISOAbcb1b (Mus musculus)6480464CTDBenzo(a)pyrene affects the expression of ABCB1B mRNAPMID:22342234
Abcb1bincreases expressionISOAbcb1b (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of ABCB1B mRNAPMID:19770486 PMID:22228805
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