GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Kras | affects methylation | ISO | KRAS (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of KRAS promoter | PMID:27901495 | Kras | increases expression | ISO | Kras (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of KRAS mRNA | PMID:22228805 | Kras | increases mutagenesis | ISO | Kras (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased mutagenesis of KRAS gene | PMID:19658153 PMID:8571376 PMID:8761429 PMID:9659573 | |
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