GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ednrb | affects methylation | ISO | EDNRB (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of EDNRB 5' UTR; Benzo(a)pyrene affects the methylation of EDNRB promoter | PMID:27901495 | Ednrb | decreases expression | ISO | Ednrb (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of EDNRB mRNA | PMID:22228805 PMID:22610609 | Ednrb | increases expression | ISO | Ednrb (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of EDNRB mRNA | PMID:19770486 PMID:21964900 PMID:32417428 | Ednrb | increases methylation | ISO | EDNRB (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased methylation of EDNRB exon | PMID:27901495 | Ednrb | multiple interactions | ISO | Ednrb (Mus musculus) | 6480464 | CTD | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of EDNRB mRNA | PMID:27858113 | |
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