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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2261
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Camk2a
Name: calcium/calmodulin-dependent protein kinase II alpha
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Camk2aincreases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of CAMK2A mRNAPMID:21839799
Camk2aaffects methylationISOCAMK2A (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of CAMK2A intronPMID:30157460
Camk2aincreases expressionISOCAMK2A (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of CAMK2A mRNAPMID:35870112
Camk2aincreases methylationISOCAMK2A (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of CAMK2A promoterPMID:27901495
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