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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1315959 Species: Mus musculus RGD Object: Gene Symbol: Wnt10a Name: wingless related MMTV integration site 10a

Acc ID: CHEBI:29865 Term: benzo[a]pyrene Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings. CasRN: 50-32-8 Chemical ID: MESH:D001564

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Benzo(a)pyrene promotes the reaction [AHR protein binds to WNT10A promoter]	PMID:19654925
decreases expression	EXP		6480464	CTD	Benzo(a)pyrene results in decreased expression of WNT10A mRNA	PMID:22610609