GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pkhd1 | decreases expression | ISO | PKHD1 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of PKHD1 mRNA | PMID:32234424 | Pkhd1 | decreases expression | ISO | Pkhd1 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of PKHD1 mRNA | PMID:19770486 PMID:21715664 | Pkhd1 | decreases methylation | ISO | PKHD1 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased methylation of PKHD1 5' UTR | PMID:27901495 | Pkhd1 | increases methylation | ISO | PKHD1 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased methylation of PKHD1 promoter | PMID:27901495 | Pkhd1 | increases mutagenesis | ISO | PKHD1 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased mutagenesis of PKHD1 gene | PMID:25435355 | |
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