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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308281 Species: Rattus norvegicus RGD Object: Gene Symbol: Hif1an Name: hypoxia-inducible factor 1, alpha subunit inhibitor

Acc ID: CHEBI:29699 Term: tunicamycin Definition: A mixture of antiviral nucleoside antibiotics produced by Streptomyces lysosuperificus. It contains at least 10 homologues comprising uracil, N-acetylglucosamine, an 11-carbon aminodialdose called tunicamine, and a fatty acid linked to the amino group of the tunicamine. The homologues vary in the composition of the fatty acid moiety. CasRN: 11089-65-9 Chemical ID: MESH:D014415

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:1550949	6480464	CTD	Tunicamycin results in decreased expression of HIF1AN mRNA	PMID:17127020