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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 67383
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prkcd
Name: protein kinase C, delta
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prkcdmultiple interactionsEXP 6480464CTDrottlerin inhibits the reaction [sodium arsenite results in increased phosphorylation of PRKCD protein]; sodium arsenite results in increased expression of and results in increased phosphorylation of PRKCD protein; Taurine inhibits the reaction [sodium arsenite results in increased expression of and results in increased phosphorylation of PRKCD protein]PMID:20830294
Prkcdaffects expressionISOPRKCD (Homo sapiens)6480464CTDsodium arsenite affects the expression of PRKCD proteinPMID:20082316
Prkcddecreases phosphorylationISOPRKCD (Homo sapiens)6480464CTDsodium arsenite results in decreased phosphorylation of PRKCD proteinPMID:20082316
Prkcdincreases expressionISOPRKCD (Homo sapiens)6480464CTDsodium arsenite results in increased expression of PRKCD mRNAPMID:12016162 PMID:12377979
Prkcdmultiple interactionsISOPRKCD (Homo sapiens)6480464CTDRTKI cpd inhibits the reaction [sodium arsenite affects the expression of PRKCD protein]; RTKI cpd inhibits the reaction [sodium arsenite results in decreased phosphorylation of PRKCD protein]; sodium arsenite promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of PRKCD protein]; sodium arsenite promotes the reaction [Ethanol results in increased phosphorylation of PRKCD protein]; sodium arsenite promotes the reaction [Sirolimus results in decreased phosphorylation of PRKCD protein]PMID:18182400 PMID:20082316
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