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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3932
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ucp2
Name: uncoupling protein 2
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ucp2decreases expressionEXP 6480464CTDsodium arsenite results in decreased expression of UCP2 mRNA; sodium arsenite results in decreased expression of UCP2 proteinPMID:25764338 PMID:28225195
Ucp2multiple interactionsEXP 6480464CTD3,4-dihydroxyphenylethanol inhibits the reaction [sodium arsenite results in decreased expression of UCP2 mRNA]PMID:28225195
Ucp2decreases expressionISOUcp2 (Mus musculus)6480464CTDsodium arsenite results in decreased expression of UCP2 mRNAPMID:31532247
Ucp2increases expressionISOUCP2 (Homo sapiens)6480464CTDsodium arsenite results in increased expression of UCP2 mRNAPMID:28229933
Ucp2multiple interactionsISOUcp2 (Mus musculus)6480464CTD[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of UCP2 mRNAPMID:34876320
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