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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3908
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tsc2
Name: TSC complex subunit 2
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tsc2affects localizationISOTSC2 (Homo sapiens)6480464CTDsodium arsenite affects the localization of TSC2 proteinPMID:33888601
Tsc2decreases expressionISOTSC2 (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of TSC2 mRNA; sodium arsenite results in decreased expression of TSC2 proteinPMID:12760830 PMID:30528433
Tsc2multiple interactionsISOTSC2 (Homo sapiens)6480464CTDHDLBP protein affects the reaction [sodium arsenite affects the localization of TSC2 protein]PMID:33888601
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