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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3343
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Plau
Name: plasminogen activator, urokinase
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Plauincreases expressionEXP 6480464CTDsodium arsenite results in increased expression of PLAU proteinPMID:21167264
Plaudecreases expressionISOPLAU (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of PLAU mRNAPMID:12016162 PMID:25493608
Plauincreases expressionISOPLAU (Homo sapiens)6480464CTDsodium arsenite results in increased expression of PLAU mRNA; sodium arsenite results in increased expression of PLAU proteinPMID:21167264 PMID:29301061
Plaumultiple interactionsISOPLAU (Homo sapiens)6480464CTDdecitabine inhibits the reaction [sodium arsenite results in increased expression of PLAU mRNA]; decitabine inhibits the reaction [sodium arsenite results in increased expression of PLAU protein]; U 0126 inhibits the reaction [sodium arsenite results in increased expression of PLAU mRNA]; U 0126 inhibits the reaction [sodium arsenite results in increased expression of PLAU protein]PMID:21167264
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