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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3336
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pklr
Name: pyruvate kinase L/R
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pklrdecreases expressionEXP 6480464CTDsodium arsenite results in decreased expression of PKLR mRNAPMID:35314868
Pklrincreases expressionEXP 6480464CTDsodium arsenite results in increased expression of PKLR proteinPMID:29459688
Pklrdecreases expressionISOPklr (Mus musculus)6480464CTDsodium arsenite results in decreased expression of PKLR mRNAPMID:37682722
Pklrdecreases expressionISOPKLR (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of PKLR mRNAPMID:17879257 PMID:29301061
Pklrincreases expressionISOPKLR (Homo sapiens)6480464CTDsodium arsenite results in increased expression of PKLR mRNAPMID:23648393
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