GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cd44 | affects methylation | ISO | CD44 (Homo sapiens) | 6480464 | CTD | sodium arsenite affects the methylation of CD44 gene | PMID:28589171 | Cd44 | decreases expression | ISO | CD44 (Homo sapiens) | 6480464 | CTD | sodium arsenite results in decreased expression of CD44 mRNA | PMID:25879800 | Cd44 | increases expression | ISO | Cd44 (Mus musculus) | 6480464 | CTD | sodium arsenite results in increased expression of CD44 mRNA | PMID:33957193 | Cd44 | increases expression | ISO | CD44 (Homo sapiens) | 6480464 | CTD | sodium arsenite results in increased expression of CD44 protein | PMID:23549458 PMID:32844245 | Cd44 | increases stability | ISO | CD44 (Homo sapiens) | 6480464 | CTD | sodium arsenite results in increased stability of CD44 mRNA | PMID:25493608 | Cd44 | multiple interactions | ISO | CD44 (Homo sapiens) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein]]; [Genistein co-treated with Lapatinib] inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein]; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein; CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein]; ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein]; Genistein inhibits the reaction [ERBB2 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein]]; Lapatinib inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein]; Lapatinib inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein]]; reparixin inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein]; SNAI1 protein affects the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein]; stattic inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein]; stattic inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein]]; U 0126 inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein]; U 0126 inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein]] | PMID:33396024 | | ||||||||||||||||||||||
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