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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:2965
Term: BQ 123
Definition: A cyclic peptide that has formula C31H42N6O7.
Chemical ID: MESH:C072247
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2multiple interactionsEXP 6480464CTD[cyclo(Trp-Asp-Pro-Val-Leu) binds to and results in decreased activity of EDNRA protein] which results in decreased expression of BCL2 proteinPMID:14736733
Bcl2multiple interactionsISOBCL2 (Homo sapiens)6480464CTD[cyclo(Trp-Asp-Pro-Val-Leu) co-treated with BQ 788] inhibits the reaction [EDN1 protein results in increased expression of BCL2 protein]PMID:20369390
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