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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3554
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ren
Name: renin
Acc ID: CHEBI:29320
Term: calcium(0)
Definition: An elemental calcium that has formula Ca.
Chemical ID: MESH:D002118
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rendecreases secretionEXP 6480464CTDCalcium results in decreased secretion of REN proteinPMID:9618396
Renmultiple interactionsEXP 6480464CTD[[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein; ML 7 inhibits the reaction [Calcium results in decreased secretion of REN protein]PMID:9618396
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