GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfe2l2 | affects localization | EXP | | 6480464 | CTD | Ascorbic Acid affects the localization of NFE2L2 protein | PMID:23027624 PMID:26921358 | Nfe2l2 | increases expression | EXP | | 6480464 | CTD | Ascorbic Acid results in increased expression of NFE2L2 protein | PMID:22008531 PMID:23027624 | Nfe2l2 | multiple interactions | EXP | | 6480464 | CTD | [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NFE2L2 protein]; Ascorbic Acid inhibits the reaction [Arsenic Trioxide results in decreased expression of NFE2L2 mRNA]; Ascorbic Acid inhibits the reaction [Estradiol affects the localization of NFE2L2 protein]; Ascorbic Acid inhibits the reaction [Estradiol inhibits the reaction [NFE2L2 protein binds to SOD3 promoter]]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of NFE2L2 mRNA]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of NFE2L2 protein]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of NFE2L2 mRNA]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of NFE2L2 protein]; Ascorbic Acid promotes the reaction [Cadmium results in increased expression of NFE2L2 protein]; Ascorbic Acid promotes the reaction [Fluorouracil affects the localization of NFE2L2 protein] | PMID:22008531 PMID:23027624 PMID:23492819 PMID:26921358 PMID:29297235 PMID:29663635 PMID:29940330 PMID:31585129 | Nfe2l2 | increases expression | ISO | NFE2L2 (Homo sapiens) | 6480464 | CTD | Ascorbic Acid results in increased expression of NFE2L2 mRNA; Ascorbic Acid results in increased expression of NFE2L2 protein | PMID:31610155 | Nfe2l2 | multiple interactions | ISO | NFE2L2 (Homo sapiens) | 6480464 | CTD | [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with ferulic acid] promotes the reaction [[Ozone co-treated with Oxygen] results in increased localization of NFE2L2 protein]; [lead acetate results in increased abundance of Lead] inhibits the reaction [Ascorbic Acid results in increased expression of NFE2L2 protein]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of NFE2L2 mRNA]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of NFE2L2 protein]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of NFE2L2 protein]; Ascorbic Acid inhibits the reaction [Resveratrol results in increased activity of NFE2L2 promoter]; Ascorbic Acid promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NFE2L2 mRNA] | PMID:21199573 PMID:23492819 PMID:25130429 PMID:26270818 PMID:28285367 PMID:31610155 | Nfe2l2 | multiple interactions | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | Ascorbic Acid inhibits the reaction [Diquat results in decreased expression of NFE2L2 protein] | PMID:33475796 | | ||||||||||||||||||||||
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