GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bcl2 | multiple interactions | EXP | | 6480464 | CTD | [alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 mRNA]; Ascorbic Acid inhibits the reaction [Humic Substances results in decreased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Ascorbic Acid promotes the reaction [lead acetate results in increased expression of BCL2 protein] | PMID:17959157 PMID:18683188 PMID:18758938 PMID:21262251 PMID:29297235 | Bcl2 | decreases expression | ISO | BCL2 (Homo sapiens) | 6480464 | CTD | Ascorbic Acid results in decreased expression of BCL2 mRNA | PMID:21919647 | Bcl2 | increases abundance | ISO | BCL2 (Homo sapiens) | 6480464 | CTD | BCL2 protein results in increased abundance of Ascorbic Acid | PMID:15449323 | Bcl2 | multiple interactions | ISO | Bcl2 (Mus musculus) | 6480464 | CTD | Ascorbic Acid inhibits the reaction [glycidamide results in decreased expression of BCL2 mRNA] | PMID:32632975 | Bcl2 | multiple interactions | ISO | BCL2 (Homo sapiens) | 6480464 | CTD | [arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BCL2 protein; [Ascorbic Acid co-treated with Quartz] results in increased expression of BCL2 mRNA; Ascorbic Acid inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in decreased expression of BCL2 mRNA]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in decreased expression of BCL2 protein] | PMID:17166419 PMID:22245848 PMID:24126434 PMID:27381660 | |
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