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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1593265
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atm
Name: ATM serine/threonine kinase
Acc ID: CHEBI:29073
Term: L-ascorbic acid
Definition: The L-enantiomer of ascorbic acid and conjugate acid of L-ascorbate.
Chemical ID: MESH:D001205
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atmmultiple interactionsISOAtm (Mus musculus)6480464CTD[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ATM mRNAPMID:17917374
Atmmultiple interactionsISOATM (Homo sapiens)6480464CTDAscorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of ATM protein modified form]PMID:25977998
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