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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71101
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc3
Name: ATP binding cassette subfamily C member 3
Acc ID: CHEBI:28971
Term: ampicillin
Definition: A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-phenylacetamido group.
Chemical ID: MESH:D000667
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc3decreases expressionISOABCC3 (Homo sapiens)6480464CTDAmpicillin results in decreased expression of ABCC3 mRNAPMID:21632981
Abcc3multiple interactionsISOAbcc3 (Mus musculus)6480464CTD[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC3 mRNAPMID:36464106
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