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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620944
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp7
Name: caspase 7
Acc ID: CHEBI:28955
Term: 2-methoxy-17beta-estradiol
Definition: A 17beta-hydroxy steroid, being 17beta-estradiol methoxylated at C-2.
Chemical ID: MESH:C022830
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp7increases expressionISOCASP7 (Homo sapiens)6480464CTD2-Methoxyestradiol results in increased expression of CASP7 protein modified formPMID:23967052
Casp7multiple interactionsISOCASP7 (Homo sapiens)6480464CTDArsenic Trioxide promotes the reaction [2-Methoxyestradiol results in increased expression of CASP7 protein modified form]PMID:23967052
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