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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdh1
Name: cadherin 1
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdh1increases expressionISOCDH1 (Homo sapiens)6480464CTDAcetylcysteine results in increased expression of CDH1 proteinPMID:34687772
Cdh1multiple interactionsISOCDH1 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CDH1 protein]; Acetylcysteine inhibits the reaction [DDT results in decreased expression of CDH1 mRNA]; Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [nickel chloride results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [nickel chloride results in increased methylation of CDH1 promoter]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of CDH1 protein]PMID:18791180 PMID:22648416 PMID:24820114 PMID:28284859 PMID:32687844 PMID:32687961 PMID:34687772
Cdh1multiple interactionsISOCdh1 (Mus musculus)6480464CTDAcetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [SHC1 protein results in decreased expression of CDH1 protein]PMID:32659284
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