GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tgfb1 | multiple interactions | EXP | | 6480464 | CTD | Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of TGFB1 mRNA]; Acetylcysteine inhibits the reaction [Glucose results in increased expression of TGFB1 mRNA]; Acetylcysteine inhibits the reaction [Glucose results in increased expression of TGFB1 protein] | PMID:23159718 PMID:36493885 | Tgfb1 | decreases expression | ISO | TGFB1 (Homo sapiens) | 6480464 | CTD | Acetylcysteine results in decreased expression of TGFB1 mRNA; Acetylcysteine results in decreased expression of TGFB1 protein modified form | PMID:32947957 | Tgfb1 | multiple interactions | ISO | TGFB1 (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [4-cresol sulfate results in increased expression of and results in increased secretion of TGFB1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of TGFB1 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in decreased expression of CAT mRNA]; Acetylcysteine inhibits the reaction [TGFB1 protein results in decreased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of HGF protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of NOX4 mRNA]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of VEGFA protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased secretion of IL6 protein] | PMID:16757516 PMID:21131394 PMID:23325087 PMID:26138014 PMID:30317545 PMID:30543783 | Tgfb1 | multiple interactions | ISO | Tgfb1 (Mus musculus) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of TGFB1 mRNA] | PMID:21765237 PMID:25406100 | | ||||||||||||||||||||||
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