GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Keap1 | multiple interactions | EXP | | 6480464 | CTD | Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein] | PMID:30104959 | Keap1 | multiple interactions | ISO | KEAP1 (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of KEAP1 protein]; Acetylcysteine inhibits the reaction [Indomethacin inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]] | PMID:11909699 PMID:19033392 | Keap1 | multiple interactions | ISO | Keap1 (Mus musculus) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Copper Sulfate results in decreased expression of KEAP1 mRNA]; Acetylcysteine inhibits the reaction [Copper Sulfate results in decreased expression of KEAP1 protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of KEAP1 protein] | PMID:37353053 PMID:37369159 | |
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