GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mmp9 | decreases activity | EXP | | 6480464 | CTD | Acetylcysteine results in decreased activity of MMP9 protein | PMID:15451797 | Mmp9 | multiple interactions | EXP | | 6480464 | CTD | [Ethanol co-treated with Dietary Fats co-treated with Acetylcysteine] results in increased expression of MMP9 mRNA; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [Ethanol results in increased secretion of and results in increased activity of MMP9 protein]; Acetylcysteine inhibits the reaction [RELA protein binds to MMP9 promoter]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA] | PMID:16213474 PMID:17603938 PMID:21051528 PMID:23774252 | Mmp9 | decreases activity | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | Acetylcysteine results in decreased activity of MMP9 protein | PMID:18930813 | Mmp9 | multiple interactions | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [4-aminophenylmercuriacetate results in increased activity of MMP9 protein]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of MMP9 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased secretion of MMP9 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of MMP9 protein]; Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of MMP9 protein]; Acetylcysteine inhibits the reaction [Homocysteine results in increased activity of MMP9 protein]; Acetylcysteine inhibits the reaction [Homocysteine results in increased expression of MMP9 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [Oxidopamine results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased expression of MMP9 mRNA] | PMID:15962302 PMID:16251475 PMID:17015178 PMID:19350554 PMID:19371603 PMID:19962414 PMID:26514923 PMID:30766661 PMID:33437163 PMID:35065218 | Mmp9 | multiple interactions | ISO | Mmp9 (Mus musculus) | 6480464 | CTD | Acetylcysteine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA] | PMID:15557194 PMID:19962414 | | ||||||||||||||||||||||
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