GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mmp1 | multiple interactions | ISO | MMP1 (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein]; Acetylcysteine inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of MMP1 mRNA]; Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of MMP1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA] | PMID:17449795 PMID:19136476 PMID:21635667 PMID:29731195 | | ||||||||||||||||||||||
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