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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfe2l2
Name: NFE2 like bZIP transcription factor 2
Acc ID: CHEBI:28925
Term: mechlorethamine
Definition: A nitrogen mustard that has formula C5H11Cl2N.
Chemical ID: MESH:D008466
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2affects response to substanceISONfe2l2 (Mus musculus)6480464CTDNFE2L2 gene mutant form affects the susceptibility to MechlorethaminePMID:26454883
Nfe2l2decreases response to substanceISONfe2l2 (Mus musculus)6480464CTDNFE2L2 protein results in decreased susceptibility to MechlorethaminePMID:20932822
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