Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	1310198
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Polr2j
Name:	RNA polymerase II subunit J

Acc ID:	CHEBI:28925
Term:	mechlorethamine
Definition:	A nitrogen mustard that has formula C5H11Cl2N.
Chemical ID:	MESH:D008466

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Polr2j	decreases expression	ISO	Polr2j (Mus musculus)	6480464	CTD	Mechlorethamine results in decreased expression of POLR2J mRNA	PMID:17107856

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.