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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61296
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aoc1
Name: amine oxidase, copper containing 1
Acc ID: CHEBI:28918
Term: (R)-adrenaline
Definition: The R-enantiomer of adrenaline. It is a hormone secreted by the adrenal glands resulting in the 'fight-or-flight' response.
Chemical ID: MESH:D004837
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aoc1increases activityEXP 6480464CTDEpinephrine results in increased activity of AOC1 proteinPMID:2860926
Aoc1multiple interactionsEXP 6480464CTDCycloheximide inhibits the reaction [Epinephrine results in increased activity of AOC1 protein]; Dactinomycin inhibits the reaction [Epinephrine results in increased activity of AOC1 protein]; Timolol inhibits the reaction [Epinephrine results in increased activity of AOC1 protein]PMID:2860926
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