GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ins2 | decreases expression | ISO | INS (Homo sapiens) | 6480464 | CTD | Epinephrine results in decreased expression of INS protein | PMID:6018752 PMID:6314140 | Ins2 | multiple interactions | ISO | INS (Homo sapiens) | 6480464 | CTD | [Epinephrine co-treated with INS protein] results in increased phosphorylation of AKT1 protein; Butoxamine inhibits the reaction [Epinephrine results in decreased expression of INS protein]; Pentolinium Tartrate inhibits the reaction [Epinephrine results in decreased secretion of INS protein]; Propranolol inhibits the reaction [Epinephrine results in decreased expression of INS protein] | PMID:1218171 PMID:32305330 PMID:6018752 | |
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