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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2061
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adrb3
Name: adrenoceptor beta 3
Acc ID: CHEBI:28918
Term: (R)-adrenaline
Definition: The R-enantiomer of adrenaline. It is a hormone secreted by the adrenal glands resulting in the 'fight-or-flight' response.
Chemical ID: MESH:D004837
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adrb3multiple interactionsEXP 6480464CTDEpinephrine binds to and results in increased activity of ADRB3 proteinPMID:7815362
Adrb3multiple interactionsISOADRB3 (Homo sapiens)6480464CTD[Epinephrine binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; Epinephrine binds to and results in increased activity of ADRB3 protein; Epinephrine inhibits the reaction [cyanopindolol binds to ADRB3 protein]PMID:14730417 PMID:1682311
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