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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61855
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gabra1
Name: gamma-aminobutyric acid type A receptor subunit alpha 1
Acc ID: CHEBI:28885
Term: butan-1-ol
Definition: A primary alcohol that is butane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group. It it produced in small amounts in humans by the gut microbes.
Chemical ID: MESH:D020001
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gabra1increases activityISOGabra1 (Mus musculus)6480464CTD1-Butanol results in increased activity of GABRA1 proteinPMID:16807363
Gabra1multiple interactionsISOGABRA1 (Homo sapiens)6480464CTD1-Butanol affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]]PMID:11137757
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