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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3772
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Stat3
Name: signal transducer and activator of transcription 3
Acc ID: CHEBI:28865
Term: taurocholic acid
Definition: A bile acid taurine conjugate of cholic acid that usually occurs as the sodium salt of bile in mammals.
Chemical ID: MESH:D013656
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Stat3increases phosphorylationISOSTAT3 (Homo sapiens)6480464CTDTaurocholic Acid results in increased phosphorylation of STAT3 proteinPMID:18512153
Stat3multiple interactionsISOSTAT3 (Homo sapiens)6480464CTDsorafenib inhibits the reaction [Taurocholic Acid results in increased phosphorylation of STAT3 protein]PMID:18512153
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