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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620944
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp7
Name: caspase 7
Acc ID: CHEBI:28863
Term: flavanones
Definition: Members of the class of flavans with a 3,4-dihydro-2-aryl-2H-1-benzopyran-4-one skeleton and its substituted derivatives.
Chemical ID: MESH:D044950
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp7increases cleavageISOCASP7 (Homo sapiens)6480464CTDFlavanones results in increased cleavage of CASP7 proteinPMID:21616090
Casp7multiple interactionsISOCASP7 (Homo sapiens)6480464CTD2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one promotes the reaction [Flavanones results in increased cleavage of CASP7 protein]; CDKN1A gene mutant form promotes the reaction [Flavanones results in increased cleavage of CASP7 protein]; PI103 promotes the reaction [Flavanones results in increased cleavage of CASP7 protein]; TP53 gene mutant form promotes the reaction [Flavanones results in increased cleavage of CASP7 protein]; U 0126 promotes the reaction [Flavanones results in increased cleavage of CASP7 protein]PMID:21616090
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