GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552629
Species: Mus musculus
RGD Object: Gene
Symbol: Nr1i3
Name: nuclear receptor subfamily 1, group I, member 3
Acc ID: CHEBI:28853
Term: isopimpinellin
Definition: A psoralen that has formula C13H10O5.
CasRN: 482-27-9
Chemical ID: MESH:C015304
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDisopimpinellin inhibits the reaction [Androstenedione inhibits the reaction [NR1I3 protein binds to NCOA1 protein]]

isopimpinellin inhibits the reaction [Androstenedione results in decreased activity of NR1I3 protein]

isopimpinellin promotes the reaction [NR1I3 protein binds to NCOA1 protein]

NR1I3 protein affects the reaction [isopimpinellin results in increased expression of CYP2B10 mRNA]

PMID:18692084
increases activityEXP 6480464CTDisopimpinellin results in increased activity of NR1I3 protein

PMID:18692084
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