GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Akt1 | decreases phosphorylation | EXP | | 6480464 | CTD | Fructose results in decreased phosphorylation of AKT1 protein | PMID:18497449 PMID:19008412 PMID:22426011 PMID:24704288 | Akt1 | increases phosphorylation | EXP | | 6480464 | CTD | Fructose results in increased phosphorylation of AKT1 protein | PMID:23533474 | Akt1 | multiple interactions | EXP | | 6480464 | CTD | [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased expression of AKT1 protein]; [Fructose co-treated with Dietary Fats] results in decreased expression of and results in decreased phosphorylation of AKT1 protein; [Fructose co-treated with Oleanolic Acid] results in increased expression of AKT1 mRNA; NOS3 protein inhibits the reaction [Fructose results in decreased phosphorylation of AKT1 protein]; Quercetin inhibits the reaction [Fructose results in decreased phosphorylation of AKT1 protein]; Quercetin inhibits the reaction [Fructose results in increased phosphorylation of AKT1 protein]; Rutin inhibits the reaction [Fructose results in decreased phosphorylation of AKT1 protein] | PMID:19008412 PMID:22426011 PMID:23533474 PMID:24704288 PMID:32259528 | | ||||||||||||||||||||||
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