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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2070
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Agtr1a
Name: angiotensin II receptor, type 1a
Acc ID: CHEBI:28757
Term: fructose
Definition: A ketohexose that is an isomer of glucose.
Chemical ID: MESH:D005632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agtr1aincreases expressionEXP 6480464CTDFructose results in increased expression of AGTR1A mRNAPMID:17587757 PMID:18360027 PMID:30710622
Agtr1amultiple interactionsEXP 6480464CTDAPLN protein modified form inhibits the reaction [Fructose results in increased expression of AGTR1A mRNA]; INS protein inhibits the reaction [Fructose results in increased expression of AGTR1A mRNA]PMID:18360027 PMID:30710622
Agtr1aincreases expressionISOAGTR1 (Homo sapiens)6480464CTDFructose results in increased expression of AGTR1 mRNAPMID:31655124
Agtr1aincreases expressionISOAgtr1a (Mus musculus)6480464CTDFructose results in increased expression of AGTR1A mRNAPMID:16843071
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