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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628641
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptger4
Name: prostaglandin E receptor 4
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptger4decreases expressionISOPTGER4 (Homo sapiens)6480464CTDDoxorubicin results in decreased expression of PTGER4 mRNAPMID:29803840
Ptger4multiple interactionsISOPtger4 (Mus musculus)6480464CTD[Doxorubicin co-treated with PTGS2 protein] results in increased expression of PTGER4 mRNA; [Doxorubicin co-treated with PTGS2 protein] results in increased expression of PTGER4 proteinPMID:19643929
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