GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Slc11a2 | decreases expression | EXP | | 6480464 | CTD | Doxorubicin results in decreased expression of SLC11A2 mRNA | PMID:19915844 | Slc11a2 | increases expression | EXP | | 6480464 | CTD | Doxorubicin results in increased expression of SLC11A2 mRNA; Doxorubicin results in increased expression of SLC11A2 protein | PMID:24089420 | Slc11a2 | multiple interactions | EXP | | 6480464 | CTD | [Deferoxamine promotes the reaction [Doxorubicin results in increased expression of SLC11A2 protein]] which results in increased uptake of Copper; [Doxorubicin results in increased expression of SLC11A2 protein] which results in increased uptake of Iron; Deferoxamine promotes the reaction [Doxorubicin results in increased expression of SLC11A2 mRNA]; Deferoxamine promotes the reaction [Doxorubicin results in increased expression of SLC11A2 protein] | PMID:24089420 | Slc11a2 | decreases expression | ISO | Slc11a2 (Mus musculus) | 6480464 | CTD | Doxorubicin results in decreased expression of SLC11A2 mRNA; Doxorubicin results in decreased expression of SLC11A2 protein | PMID:35667395 | | ||||||||||||||||||||||
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